The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2013

Filed:

Jun. 16, 2006
Applicant:

F. Nicholas Franano, Kansas City, MO (US);

Inventor:

F. Nicholas Franano, Kansas City, MO (US);

Assignee:

Proteon Therapeutics, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61K 38/48 (2006.01); A61K 38/55 (2006.01); A61K 35/39 (2006.01); C12Q 1/34 (2006.01); C12Q 1/37 (2006.01); A61M 25/06 (2006.01); A61M 29/02 (2006.01); A61M 31/00 (2006.01); A61M 25/085 (2006.01); A61M 25/10 (2013.01); A61M 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods for treating an obstructed biological conduit that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes prophylactically dilating a section of conduit to minimize the risk of obstruction formation.


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