The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2013
Filed:
Jun. 06, 2007
Applicants:
Annibale Salvi, Milan, IT;
Antonio Nardi, Milan, IT;
Bruno DE Angelis, Milan, IT;
Inventors:
Assignee:
Laboratorio Chimico Internazionale S.p.A., Milan, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 205/00 (2006.01); C07C 207/00 (2006.01); C07C 229/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to the preparation of (R)-(−)-3-(carbamoylmethyl)-5-methylhexanoic acid, in particular, the resolution of the acid racemate by means of salification with optically active amines and subsequent acidification to give the (R) enantiomer of the acid; this invention also concerns the salt intermediates formed with said amines and the conversion of said (R)-(−)-3-(carbamoylmethyl)-5-methylhexanoic acid into biologically active molecules such as pregabalin.