The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2013

Filed:

May. 14, 2012
Applicants:

Matthew Burger, Emeryville, CA (US);

Zhi-jie NI, Freemont, CA (US);

Sabina Pecchi, Oakland, CA (US);

Gordana Ataliah, Emeryville, CA (US);

Sarah Bartulis, Emeryville, CA (US);

Kelly Frazier, Emeryville, CA (US);

Aaron Smith, Freemont, CA (US);

Joelle Verhagen, Emeryville, CA (US);

Yanchen Zhang, Emeryville, CA (US);

Allan Wagman, Belmont, CA (US);

Simon NG, Walnut Creek, CA (US);

Keith Pfister, San Ramon, CA (US);

Daniel J. Poon, Piedmont, CA (US);

Alicia Louie, Emeryville, CA (US);

Teresa Pick, Danville, CA (US);

Paul Barsanti, Pleasant Hill, CA (US);

Edwin Iwanowicz, Emeryville, CA (US);

Wendy Fantl, Emeryville, CA (US);

Thomas Hendrickson, Emeryville, CA (US);

Mark Knapp, Oakland, CA (US);

Hanne Meritt, Emeryville, CA (US);

Charles Voliva, Emeryville, CA (US);

Marion Wiesmann, Bottmingen, CH;

Xiahua Xin, Emeryville, CA (US);

Inventors:

Matthew Burger, Emeryville, CA (US);

Zhi-Jie Ni, Freemont, CA (US);

Sabina Pecchi, Oakland, CA (US);

Gordana Ataliah, Emeryville, CA (US);

Sarah Bartulis, Emeryville, CA (US);

Kelly Frazier, Emeryville, CA (US);

Aaron Smith, Freemont, CA (US);

Joelle Verhagen, Emeryville, CA (US);

Yanchen Zhang, Emeryville, CA (US);

Allan Wagman, Belmont, CA (US);

Simon Ng, Walnut Creek, CA (US);

Keith Pfister, San Ramon, CA (US);

Daniel J. Poon, Piedmont, CA (US);

Alicia Louie, Emeryville, CA (US);

Teresa Pick, Danville, CA (US);

Paul Barsanti, Pleasant Hill, CA (US);

Edwin Iwanowicz, Emeryville, CA (US);

Wendy Fantl, Emeryville, CA (US);

Thomas Hendrickson, Emeryville, CA (US);

Mark Knapp, Oakland, CA (US);

Hanne Meritt, Emeryville, CA (US);

Charles Voliva, Emeryville, CA (US);

Marion Wiesmann, Bottmingen, CH;

Xiahua Xin, Emeryville, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.


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