The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8563540 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 22, 2013

Filed:

Apr. 01, 2013
Applicant:

Genetech, Inc., South San Francisco, CA (US);

Inventors:

Georgette Castanedo, Redwood City, CA (US);

Bryan Chan, San Carlos, CA (US);

Matthew C. Lucas, Nutley, NJ (US);

Brian Safina, Redwood City, CA (US);

Daniel P. Sutherlin, Burlingame, CA (US);

Zachary Sweeney, Redwood City, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/397 (2006.01); A61K 31/5377 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.


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