The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Oct. 10, 2008
Calum Eric Macaulay, Vancouver, CA;
Piotr Dubrowski, Vancouver, CA;
Martial Guillaud, Gibsons, CA;
Mehrnoush Khojasteh, Vancouver, CA;
Calum Eric MacAulay, Vancouver, CA;
Piotr Dubrowski, Vancouver, CA;
Martial Guillaud, Gibsons, CA;
Mehrnoush Khojasteh, Vancouver, CA;
British Columbia Cancer Agency Branch, Vancouver, CA;
The University of British Columbia, Vancouver, CA;
Abstract
Systems and methods for the quantitative automated analysis of pathology samples identify groups of spatially-associated similar cells. Cells may be identified as belonging to a group on the basis of spatial location and biomarkers. In some embodiments the biomarkers are multicolour fluorescence in situ hybridization (FISH) signals. Characteristics of the cells in a group may be combined to provide quantitative FISH results that may compensate for variations and artefacts such as thin sectioning that can result in the loss of information due to damage. In heterogeneous tissue samples, grouping cells can permit quantitative results regarding pathological cells to be extracted despite the presences of infiltrating non pathological cells.