The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Apr. 10, 2009
Christian Andrew Baumann, Exton, PA (US);
Michael David Gaul, Yardley, PA (US);
Dana L. Johnson, Upper Black Eddy, PA (US);
Robert W. Tuman, Chalfont, PA (US);
Christian Andrew Baumann, Exton, PA (US);
Michael David Gaul, Yardley, PA (US);
Dana L. Johnson, Upper Black Eddy, PA (US);
Robert W. Tuman, Chalfont, PA (US);
Janssen Pharmaceutica, N.V., Beerse, BE;
Abstract
The invention is directed to a method of inhibiting FLT3 tyrosine kinase activity or expression or reducing FLT3 kinase activity or expression in a cell or a subject comprising the administration of a farnesyl transferase inhibitor and a FLT3 kinase inhibitor selected from compounds of Formula I': Included within the present invention is both prophylactic and therapeutic methods for treating a subject at risk of (or susceptible to) developing a cell proliferative disorder or a disorder related to FLT3.