The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Aug. 22, 2005
Shaomeng Wang, Saline, MI (US);
Guoping Wang, Ann Arbor, MI (US);
Guozhi Tang, Ann Arbor, MI (US);
Renxiao Wang, Ann Arbor, MI (US);
Zaneta Nikolovska-coleska, Ann Arbor, MI (US);
Dajun Yang, Rockville, MD (US);
Liang Xu, Ann Arbor, MI (US);
Shaomeng Wang, Saline, MI (US);
Guoping Wang, Ann Arbor, MI (US);
Guozhi Tang, Ann Arbor, MI (US);
Renxiao Wang, Ann Arbor, MI (US);
Zaneta Nikolovska-Coleska, Ann Arbor, MI (US);
Dajun Yang, Rockville, MD (US);
Liang Xu, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Abstract
The invention relates to small molecules which function as inhibitors of anti-apoptotic Bcl-2 family member proteins (e.g., Bcl-2 and Bcl-xL). The invention also relates to the use of these compounds for inducing apoptotic cell death and sensitizing cells to the induction of apoptotic cell death.