The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Mar. 15, 2010
Kai Fan, Jiulongpo Chongqing, CN;
Zhiquan Zhao, Jiulongpo Chongqing, CN;
Yong Chen, Jiulongpo Chongqing, CN;
Chun Zhang, Jiulongpo Chongqing, CN;
Lin Wang, Jiulongpo Chongqing, CN;
Kai Fan, Jiulongpo Chongqing, CN;
Zhiquan Zhao, Jiulongpo Chongqing, CN;
Yong Chen, Jiulongpo Chongqing, CN;
Chun Zhang, Jiulongpo Chongqing, CN;
Lin Wang, Jiulongpo Chongqing, CN;
Chongqing Fagen Biomedical Inc., Jiulongpo Chongqing, CN;
Abstract
Provided is a homodimer of insulinotropic peptide analogues and method for preparation thereof and use thereof, wherein the insulinotropic peptide analogue comprises GLP-1 and Exendin-4. The homodimer of insulinotropic peptide analogues of the invention is made by conjugating two identical insulinotropic peptide analogue molecules at the C-terminal Cys residues via disulfide bond or PEG molecule. The homodimer of insulinotropic peptide analogues of the invention has superior stability and biological activity in vivo, and prolonged half-life in the circulation, and can be used for the preparation of hypoglycemic drugs.