The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Nov. 13, 2007
Applicants:
Hiroaki Suga, Tokyo, JP;
Hiroshi Murakami, Tokyo, JP;
Yuki Goto, Tokyo, JP;
Atsushi Ohta, Tokyo, JP;
Inventors:
Hiroaki Suga, Tokyo, JP;
Hiroshi Murakami, Tokyo, JP;
Yuki Goto, Tokyo, JP;
Atsushi Ohta, Tokyo, JP;
Assignee:
The University of Tokyo, Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention aims to synthesize a polypeptide having an unnatural structure at the N-terminus via a biosynthetic process by translation of amino acid sequence information encoded by a nucleic acid. A polypeptide having any amino acid at the N-terminus is synthesized by using an ARS ribozyme that catalyzes the acylation of tRNA with any amino acid to attach any amino acid to an initiator tRNA, thereby initiating a translation with the initiator tRNA.