The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Feb. 27, 2012
Alice Wang, Lafayette, CA (US);
Robert J. Lagier, San Leandro, CA (US);
Charles M. Rowland, San Francisco, CA (US);
Alice Wang, Lafayette, CA (US);
Robert J. Lagier, San Leandro, CA (US);
Charles M. Rowland, San Francisco, CA (US);
Celera Corporation, Alameda, CA (US);
Abstract
The present invention relates to a composite metastasis score ('cMS') based on expression of a 14-gene molecular signature (referred to as a metastasis score, or 'MS') in combination with progesterone receptor (PR) expression that is useful for predicting breast cancer metastasis. In preferred embodiments, the cMS is determined by applying weighted coefficients to MS and PR. The present invention provides methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information for predicting risk of breast cancer metastasis, among other embodiments.