The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2013

Filed:

Aug. 21, 2006
Applicants:

Sarah Fredriksson, Genarp, SE;

Sylvia Koivunen, Helsingborg, SE;

Fredrik Olsson, Malmö, SE;

Hanna-karin Toftevall, Eslöv, SE;

Inventors:

Sarah Fredriksson, Genarp, SE;

Sylvia Koivunen, Helsingborg, SE;

Fredrik Olsson, Malmö, SE;

Hanna-Karin Toftevall, Eslöv, SE;

Assignee:

Genovis AB, Lund, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A nano sized particle for in vitro or ex vivo biomolecule delivery to cell cultures through heat induced endosomal release comprising a superparamagnetic core coated in a heat sensitive coating, comprising membrane disruptive components and binding sites for attachment of biomolecules and markers to be delivered is provided. A method is provided for introducing the release effect of a plurality of said biomolecule and endosomal disrupture molecules by applying an alternating field to a cell culture harboring the particle described by the invention.


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