The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Mar. 14, 2008
José Angel Martínez Escribano, Madrid, ES;
Andrés Wigdorovitz, Buenos Aires, AR;
Félix Gil Dones, Madrid, ES;
Agustin Ostachuk, Buenos Aires, AR;
Mariano Pèrez Filguera, Buenos Aires, AR;
Javier Dominguez, Madrid, ES;
Carmen Núnez Serrano, Madrid, ES;
Maria Josè Dus Santos, Buentos Aires, AR;
Covadonga Alonso Marti, Madrid, ES;
José Angel Martínez Escribano, Madrid, ES;
Andrés Wigdorovitz, Buenos Aires, AR;
Félix Gil Dones, Madrid, ES;
Agustin Ostachuk, Buenos Aires, AR;
Mariano Pèrez Filguera, Buenos Aires, AR;
Javier Dominguez, Madrid, ES;
Carmen Núnez Serrano, Madrid, ES;
Maria Josè Dus Santos, Buentos Aires, AR;
Covadonga Alonso Marti, Madrid, ES;
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Madrid, ES;
Alternative Gene Expression, S.L., Madrid, ES;
Abstract
Fusion protein with directioning of vaccinal antigens toward antigen-presenting cells and the applications thereof. This invention relates to a gene construct that comprises, operatively bound, at least one nucleotide sequence (A) that encodes a polypeptide with SEQ ID NO: 1, which has a region that recognizes the β chain of the class-II DR antigen present on the surface of antigen-presenting cells; and one nucleotide sequence (B) that encodes a vaccinal antigen of interest. Moreover, this invention relates to recombinant vectors useful for the expression of the gene construct of the invention, transgenic cells and plants transformed or transfected with said vectors, fusion proteins encoded by the gene construct of the invention and vaccines that comprise said fusion proteins.