The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2013

Filed:

Jul. 28, 2000
Applicants:

Christine White, Rancho Santa Fe, CA (US);

Antonio Grillo-lopez, Rancho Santa Fe, CA (US);

Inventors:

Christine White, Rancho Santa Fe, CA (US);

Antonio Grillo-Lopez, Rancho Santa Fe, CA (US);

Assignee:

Biogen Idec Inc., Weston, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/661 (2006.01); A61K 31/664 (2006.01); A61K 31/704 (2006.01); A61K 31/56 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); Y10S 424/801 (2013.01);
Abstract

This invention concerns methods for the treatment of intermediate and high-grade non-Hodgkins lymphomas, comprising the administration of anti-CD20 monoclonal antibodies and fragments thereof. Particular embodiments include the administration of chimeric anti-CD20 antibody, either alone or in combination with radiolabeled antibodies or chemotherapy. The invention is particularly useful for lymphomas characterized by a high number of circulating B cells, possibly bone marrow involvement, bulky disease, or the involvement of extralymphatic organs or sites.


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