The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Feb. 27, 2009
Stephen D. Gillies, Carlisle, MA (US);
Nigel John Watkins, Cambridgeshire, GB;
Matthew Paul Baker, Cambridge, GB;
Kin-ming Lo, Lexington, MA (US);
Steven C. Degon, Hampton, NH (US);
Stephen D. Gillies, Carlisle, MA (US);
Nigel John Watkins, Cambridgeshire, GB;
Matthew Paul Baker, Cambridge, GB;
Kin-Ming Lo, Lexington, MA (US);
Steven C. Degon, Hampton, NH (US);
Merck Patent GmbH, Darmstadt, DE;
Abstract
Disclosed are Fc-interferon-beta (Fc-IFN-β) fusion proteins and nucleic acid molecules encoding them. The Fc-IFN-β fusion proteins include variants of the interferon-beta (IFN-β) protein that are altered to achieve enhanced biological activity, prolonged circulating half-life and greater solubility. Also disclosed are methods of producing the fusion proteins and methods of using the fusion proteins and/or nucleic acid molecules for treating diseases and conditions alleviated by the administration of interferon-beta.