The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2013
Filed:
Jul. 01, 2011
John B. Troy, Evanston, IL (US);
Samsoon Inayat, Evanston, IL (US);
Donald R. Cantrell, Evanston, IL (US);
Yan Zhao, Chicago, IL (US);
Dmitriy A. Dikin, Skokie, IL (US);
John B. Troy, Evanston, IL (US);
Samsoon Inayat, Evanston, IL (US);
Donald R. Cantrell, Evanston, IL (US);
Yan Zhao, Chicago, IL (US);
Dmitriy A. Dikin, Skokie, IL (US);
Northwestern University, Evanston, IL (US);
Abstract
A pushpen electrode is provided for electrophysiology measurements. The pushpen operation is used to impale a cell membrane in cell-attached configuration to go whole-cell without disruption of the gigaseal. The pushpen electrode has advantages over the conventional patch clamp electrode in reducing tip series resistance, increasing signal bandwidth, permitting longer-term recordings and reducing diffusion between the cytosol and the electrode solution.