The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Jun. 23, 2010
Applicants:

John Maier, Pittsburgh, PA (US);

Joseph Demuth, Naples, FL (US);

Jeffrey Cohen, Pittsburgh, PA (US);

Shona Stewart, Pittsburgh, PA (US);

Lindy Mcclelland, Rochester, NY (US);

Inventors:

John Maier, Pittsburgh, PA (US);

Joseph Demuth, Naples, FL (US);

Jeffrey Cohen, Pittsburgh, PA (US);

Shona Stewart, Pittsburgh, PA (US);

Lindy McClelland, Rochester, NY (US);

Assignee:

ChemImage Corporation, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01S 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for generating an image of a sample that is informative of the disease state of a cell in the sample. A sample including the cell is irradiated with monochromatic light. The Raman scattered light is assessed. A digital brightfield image of the Raman scattered light is generated and combined with the Raman scattered light emitted by the cell whereby the Raman scattered light is informative of the disease state of the cell in the sample. The method can also be used to determine the metabolic activity of the cell, the inflammatory status of the cell and/or the infected status of the cell in the sample.


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