The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Mar. 06, 2012
Applicants:

Gulzar Ahmed, Voorhees, NJ (US);

Henry J. Breslin, Lansdale, PA (US);

Jason Burke, Charlottesville, VA (US);

Matthew A. Curry, Coatesville, PA (US);

James L. Diebold, Eagleville, PA (US);

Bruce D. Dorsey, Ambler, PA (US);

Benjamin J. Dugan, Glen Mills, PA (US);

Daming Feng, East Windsor, NJ (US);

Diane E. Gingrich, Downingtown, PA (US);

Tao Guo, Dayton, NJ (US);

Keith S. Learn, Perkiomenville, PA (US);

Joseph Lisko, Alpharetta, GA (US);

Rong-qiang Liu, Kendall Park, NJ (US);

Eugen F. Mesaros, Wallingford, PA (US);

Karen L. Milkiewicz, Exton, PA (US);

Gregory R. Ott, Media, PA (US);

Jay P. Theroff, West Chester, PA (US);

Tho Thieu, Ambler, PA (US);

Rabindranath Tripathy, Churchville, PA (US);

Theodore L. Underiner, Malvern, PA (US);

Gregory J. Wells, West Chester, PA (US);

Craig A. Zificsak, Downingtown, PA (US);

Inventors:

Gulzar Ahmed, Voorhees, NJ (US);

Henry J. Breslin, Lansdale, PA (US);

Jason Burke, Charlottesville, VA (US);

Matthew A. Curry, Coatesville, PA (US);

James L. Diebold, Eagleville, PA (US);

Bruce D. Dorsey, Ambler, PA (US);

Benjamin J. Dugan, Glen Mills, PA (US);

Daming Feng, East Windsor, NJ (US);

Diane E. Gingrich, Downingtown, PA (US);

Tao Guo, Dayton, NJ (US);

Keith S. Learn, Perkiomenville, PA (US);

Joseph Lisko, Alpharetta, GA (US);

Rong-qiang Liu, Kendall Park, NJ (US);

Eugen F. Mesaros, Wallingford, PA (US);

Karen L. Milkiewicz, Exton, PA (US);

Gregory R. Ott, Media, PA (US);

Jay P. Theroff, West Chester, PA (US);

Tho Thieu, Ambler, PA (US);

Rabindranath Tripathy, Churchville, PA (US);

Theodore L. Underiner, Malvern, PA (US);

Gregory J. Wells, West Chester, PA (US);

Craig A. Zificsak, Downingtown, PA (US);

Assignee:

Cephalon, Inc., Frazier, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R, R, R, R, R, A, A, A, A, and A, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.


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