The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Mar. 23, 2006
Douglas J. Dellinger, Boulder, CO (US);
Zoltan Timar, Boulder, CO (US);
Agnieszka Sierzchala, Boulder, CO (US);
Geraldine Dellinger, Boulder, CO (US);
Marvin H. Caruthers, Boulder, CO (US);
Joel Myerson, Berkeley, CA (US);
Douglas J. Dellinger, Boulder, CO (US);
Zoltan Timar, Boulder, CO (US);
Agnieszka Sierzchala, Boulder, CO (US);
Geraldine Dellinger, Boulder, CO (US);
Marvin H. Caruthers, Boulder, CO (US);
Joel Myerson, Berkeley, CA (US);
Agilent Technologies, Inc., Santa Clara, CA (US);
The Regents of the University of Colorado, Denver, CO (US);
Abstract
Methods of deprotecting polynucleotides are disclosed. One aspect of the method of deprotecting polynucleotides, among others, includes: providing a polynucleotide, wherein the polynucleotide includes at least one nucleotide monomer that has at least one protecting group selected from the following: a base having a protecting group, a 2'-hydroxyl protecting group, and a combination thereof, and deprotecting at least one of the protecting groups of the polynucleotide by introducing the polynucleotide to a solution including an α-effect nucleophile.