The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Sep. 25, 2009
Applicants:

Gordon J. Freeman, Brookline, MA (US);

Rafi Ahmed, Atlanta, GA (US);

Timothy D. Jones, Cambridgeshire, GB;

Francis J. Carr, Aberdeenshire, GB;

James P. Gregson, Essex, GB;

Inventors:

Gordon J. Freeman, Brookline, MA (US);

Rafi Ahmed, Atlanta, GA (US);

Timothy D. Jones, Cambridgeshire, GB;

Francis J. Carr, Aberdeenshire, GB;

James P. Gregson, Essex, GB;

Assignees:

Emory University, Atlanta, GA (US);

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein.


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