The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Nov. 30, 2009
Christina Furebring, Lund, SE;
Anna Rosén, S. Sandby, SE;
Karin Haraldsson, Lund, SE;
Erika Gustafsson, Bjarred, SE;
Björn Ulrik Walse, Lund, SE;
Christina Furebring, Lund, SE;
Anna Rosén, S. Sandby, SE;
Karin Haraldsson, Lund, SE;
Erika Gustafsson, Bjarred, SE;
Björn Ulrik Walse, Lund, SE;
Alligator Bioscience AB, Lund, SE;
Abstract
The present invention provides a polypeptide having a biological activity of the Chemotaxis Inhibitory Protein of('CHIPS'), the polypeptide comprising or consisting of the amino acid sequence of SEQ ID NO: 2, or a fragment or variant thereof having a biological activity of CHIPS, wherein the fragment or variant retains amino acid substitutions K40E, D42V, N77H, K100R, K105R, N111 K and/or G112A relative to the wildtype CHIPS protein of SEQ ID NO:1. In one embodiment, polypeptide consists of the amino acid sequence of SEQ ID NO: 2. Related aspects of the invention provide pharmaceutical compositions comprising a polypeptide of the invention, together with methods or making and using the same.