The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Mar. 18, 2011
Laurence H. Hurley, Tucson, AZ (US);
Daruka Mahadevan, Tucson, AZ (US);
David J. Bearss, Cedar Hills, UT (US);
Hariprasad Vankayalapati, Draper, UT (US);
Sridevi Bashyam, Bangalore, IN;
Steven L. Warner, Sandy, UT (US);
James Welsh, Oro Valley, AZ (US);
Laurence H. Hurley, Tucson, AZ (US);
Daruka Mahadevan, Tucson, AZ (US);
David J. Bearss, Cedar Hills, UT (US);
Hariprasad Vankayalapati, Draper, UT (US);
Sridevi Bashyam, Bangalore, IN;
Steven L. Warner, Sandy, UT (US);
James Welsh, Oro Valley, AZ (US);
Arizona Board of Regents on behalf of the University of Arizona, Tucson, AZ (US);
Astex Pharmaceutials, Inc., Dublin, CA (US);
Abstract
Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.