The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Jan. 23, 2009
Andrey Alexandrovich Ivashchenko, Moscow, RU;
Alexander Vasilievich Ivashchenko, Encinitas, CA (US);
Nikolay Filippovich Savchuk, Rancho Santa Fe, CA (US);
Andrey Alexandrovich Ivashchenko, Moscow, RU;
Alexander Vasilievich Ivashchenko, Encinitas, CA (US);
Nikolay Filippovich Savchuk, Rancho Santa Fe, CA (US);
Avincuro Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
The present invention relates to novel substituted 3-(arylsulfonyl)pyrazolo[1,5-a]pyrimidines of general formula 1 pharmaceutically acceptable salts and/or hydrates, to novel serotonin 5-HTreceptor antagonists, to novel drug substances, pharmaceutical compositions, medicaments and methods for their preparation and use for treatment and prophylaxis of pathological states and diseases of CNS, pathogenesis of which is associated with disturbance of serotonin 5-HTreceptor activation. In compounds of general formula 1 Ar represents optionally substituted aryl or heterocyclyl; R, Rand Rindependently of each other represent hydrogen, C-Calkyl or phenyl; Rrepresents hydrogen, optionally substituted C-Calkyl, substituted hydroxyl group or substituted sulfanyl group.