The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Apr. 28, 2010
Applicants:

Minoru Koura, Higashimurayama, JP;

Hisashi Sumida, Higashimurayama, JP;

Takayuki Matsuda, Higashimurayama, JP;

Yuichiro Watanabe, Higashimurayama, JP;

Takashi Enomoto, Higashimurayama, JP;

Kimiyuki Shibuya, Higashimurayama, JP;

Sumiko Kurobuchi, Higashimurayama, JP;

Inventors:

Minoru Koura, Higashimurayama, JP;

Hisashi Sumida, Higashimurayama, JP;

Sayaka Kurobuchi, Higashimurayama, JP;

Takayuki Matsuda, Higashimurayama, JP;

Yuichiro Watanabe, Higashimurayama, JP;

Takashi Enomoto, Higashimurayama, JP;

Kimiyuki Shibuya, Higashimurayama, JP;

Assignee:

Kowa Company, Ltd., Nagoya-shi, Aichi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/551 (2006.01); C07D 233/72 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 491/048 (2006.01); C07D 491/056 (2006.01);
U.S. Cl.
CPC ...
Abstract

[Object] It is to provide a novel LXRβ agonist useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease. [Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate: (wherein, each V and W independently show N or C—R; each X and Y independently show CH, C═O, SO, etc; Z shows CH or N; each R, Rand Rindependently show a hydrogen atom, Calkyl group, etc.; Rshows Calkyl group; Rshows an optionally substituted Caryl group or an optionally substituted 5- to 11-membered heterocyclic group; Rand Rshow a hydrogen atom, etc.; L shows a Calkyl chain optionally substituted with an oxo group, etc.; and n shows any integer of 0 to 2.)


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