The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Nov. 17, 2010
Applicants:

Volker Schulze, Bergfelde, DE;

Marcus Koppitz, Berlin, DE;

Dirk Kosemund, Berlin, DE;

Benjamin Bader, Berlin, DE;

Philip Lienau, Berlin, DE;

Hans Briem, Berlin, DE;

Simon Holton, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Stefan Prechtl, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Inventors:

Volker Schulze, Bergfelde, DE;

Marcus Koppitz, Berlin, DE;

Dirk Kosemund, Berlin, DE;

Benjamin Bader, Berlin, DE;

Philip Lienau, Berlin, DE;

Hans Briem, Berlin, DE;

Simon Holton, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Stefan Prechtl, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/40 (2006.01); A01N 43/64 (2006.01); A61K 31/33 (2006.01); A61K 31/445 (2006.01); A61K 31/41 (2006.01); C07D 221/02 (2006.01); C07D 471/02 (2006.01); C07D 249/08 (2006.01); C07D 249/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors: Formula (I), in which R, R, R, R, and Rare as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis proliferative of diseases, as well as to intermediate compounds useful in the preparation of said compounds.


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