The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Oct. 28, 2010
Applicants:

Haizhou Sun, Dallas, TX (US);

Xiaoming Xu, Dallas, TX (US);

Ming Zhou, Dallas, TX (US);

Susan Harran, Dallas, TX (US);

Gunnar James Hanson, Dallas, TX (US);

Lai Wang, Dallas, TX (US);

Inventors:

Haizhou Sun, Dallas, TX (US);

Xiaoming Xu, Dallas, TX (US);

Ming Zhou, Dallas, TX (US);

Susan Harran, Dallas, TX (US);

Gunnar James Hanson, Dallas, TX (US);

Lai Wang, Dallas, TX (US);

Assignee:

Joyant Pharmaceuticals, Inc., Dallas, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/06 (2006.01); A61K 38/08 (2006.01); C07C 45/87 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.


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