The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Oct. 24, 2009
Applicants:

Oscar Azucena, Santa Cruz, CA (US);

Joel Kubby, Santa Cruz, CA (US);

Jian Cao, Stanford, CA (US);

William Sullivan, Santa Cruz, CA (US);

Inventors:

Oscar Azucena, Santa Cruz, CA (US);

Joel Kubby, Santa Cruz, CA (US);

Jian Cao, Stanford, CA (US);

William Sullivan, Santa Cruz, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 1/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of microscopic imaging of biological tissue using adaptive optics technology to improve the image focus and sharpness. Wavefront measurements are taken by using a novel method of seeding biological tissue by using a fluorescent microsphere as a 'guide star' as a natural point-source reference. The current methods are capable of improving the Strehl ratio of modern biological microscopes as much as 15 times.


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