The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Feb. 06, 2009
Hendrik Coenraad Lm Hemker, Maastricht, NL;
Pieter Wilhelm Hemker, AL Amsterdam, NL;
Hendrik Coenraad LM Hemker, Maastricht, NL;
Pieter Wilhelm Hemker, AL Amsterdam, NL;
Synapse B.V., Maastricht, NL;
Abstract
A method of determining the course of enzyme activity that is variable in time, wherein the activity is probed by conversion of a substrate of the enzyme, includes, in a selected test set up and for a determined substrate of the enzyme, determining the velocity of signal production (dF/dt) resulting from a time curve of the signal (F=f(A)) obtained from splitting the substrate when it is contacted with a determined initially fixed concentration of the enzyme (E) and providing a 'diagnostic plot' with the values of (dF/dt) against the signal (F) and determining whether the diagnostic plot is either a straight line or a parabola and in the same test conditions, for a given test sample, determining the signal production (F) resulting from splitting the substrate by the enzyme generating in and/or disappearing from the sample and providing the time curve of signal F=f(t); and transforming the obtained experimental value of the signal (F) into an ideal value (F).