The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Jul. 12, 2010
Gavin J. Gordon, West Newbury, MA (US);
Roderick V. Jensen, Pelham, MA (US);
Steven R. Gullans, Natick, MA (US);
Li-li Hsiao, Jamaica Plain, MA (US);
Raphael Bueno, Brookline, MA (US);
Gavin J. Gordon, West Newbury, MA (US);
Roderick V. Jensen, Pelham, MA (US);
Steven R. Gullans, Natick, MA (US);
Li-Li Hsiao, Jamaica Plain, MA (US);
Raphael Bueno, Brookline, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Wesleyan University, Middletown, CT (US);
Abstract
The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from tissue samples, such as cancer tissue samples. The invention also provides sets of genes that are expressed differentially in malignant pleural mesothelioma. These sets of genes can be used to discriminate between normal and malignant tissues, and between classes of malignant tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.