The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Jun. 03, 2010
Applicants:

Christian Scholz, Penzberg, DE;

Ralf Bollhagen, Penzberg, DE;

Alfred Engel, Weilheim, DE;

Elke Faatz, Huglfing, DE;

Peter Schaarschmidt, Uffing, DE;

Barbara Upmeier, Iffeldorf, DE;

Toralf Zarnt, Iffeldorf, DE;

Inventors:

Christian Scholz, Penzberg, DE;

Ralf Bollhagen, Penzberg, DE;

Alfred Engel, Weilheim, DE;

Elke Faatz, Huglfing, DE;

Peter Schaarschmidt, Uffing, DE;

Barbara Upmeier, Iffeldorf, DE;

Toralf Zarnt, Iffeldorf, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); A61K 39/20 (2006.01); C12N 7/01 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to soluble rubella E1 antigens and variants of these antigens. The antigens contain amino acids 201 to 432 or 169 to 432 and are lacking amino acids 453 to 481 as well as at least the amino acids 143 to 164. They further contain a region spanning two disulfide-bridges. The invention also relates to a recombinant DNA molecule encoding the rubella E1 antigens, the expression of rubella E1 antigens as chaperone fusion proteins and their use in a method of detecting antibodies against rubella in a sample.


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