The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Dec. 16, 2008
Applicants:

Douglas Robert Hoffman, Greenville, WI (US);

Andrea JO Smiltneek, Appleton, WI (US);

Sara Ann Carney, De Pere, WI (US);

Scott W. Wenzel, Neenah, WI (US);

David William Koenig, Menasha, WI (US);

Jeffery Richard Seidling, Appleton, WI (US);

Inventors:

Douglas Robert Hoffman, Greenville, WI (US);

Andrea Jo Smiltneek, Appleton, WI (US);

Sara Ann Carney, De Pere, WI (US);

Scott W. Wenzel, Neenah, WI (US);

David William Koenig, Menasha, WI (US);

Jeffery Richard Seidling, Appleton, WI (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61L 31/12 (2006.01); A61L 2/232 (2006.01); A01N 25/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure comprises a polymeric substrate that provides multiple releases of active agents. A substrate for multiple phase delivery of active agents is provided having a first polymer matrix layer having a first active agent disposed therein, a second polymer matrix layer having a second active agent disposed therein, and a coacervate layer disposed between the first polymer matrix layer and the second polymer matrix layer. Selected first and second active agents are included in the first and second polymer matrices such that as the first and second polymer matrices dissolve, the active agents are released. Multiple phase active agent release is achieved by constructing multiple layers of a polymer matrix containing an active agents formed with polymers having different solubility characteristics or with active agents at different concentration levels.


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