The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2013
Filed:
Oct. 13, 2011
Applicants:
Lichun Feng, Shanghai, CN;
Mengwei Huang, Shanghai, CN;
Yongfu Liu, Shanghai, CN;
Guolong Wu, Shanghai, CN;
Mingwei Zhou, Shanghai, CN;
Inventors:
Lichun Feng, Shanghai, CN;
Mengwei Huang, Shanghai, CN;
Yongfu Liu, Shanghai, CN;
Guolong Wu, Shanghai, CN;
Mingwei Zhou, Shanghai, CN;
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); C07D 215/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to compounds according to formula (I) and pharmaceutically acceptable salts or esters thereof, wherein Rto Rhave the significance given herein. The compounds are activators of AMP-activated protein kinase (AMPK) and are useful in the treatment or prophylaxis of diseases that are related to AMPK regulation, such as obesity, dyslipidemia, hyperglycemia, type 1 or type 2 diabetes and cancers.