The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2013

Filed:

Sep. 17, 2010
Applicants:

Mark Peter Bell, Craigavon, GB;

Timothy Harrison, Craigavon, GB;

Sumita Bhattacharyya, Craigavon, GB;

James Samuel Shane Rountree, Craigavon, GB;

Frank Burkamp, Craigavon, GB;

Stephen Price, Harlow, GB;

Calum Macleod, Harlow, GB;

Richard Leonard Elliott, Harlow, GB;

Phillip Smith, Harlow, GB;

Toby Jonathan Blench, Harlow, GB;

Colin Roderick O'dowd, Craigavon, GB;

Lixin Zhang, Craigavon, GB;

Graham Peter Trevitt, Craigavon, GB;

Hazel Joan Dyke, Harlow, GB;

Inventors:

Mark Peter Bell, Craigavon, GB;

Timothy Harrison, Craigavon, GB;

Sumita Bhattacharyya, Craigavon, GB;

James Samuel Shane Rountree, Craigavon, GB;

Frank Burkamp, Craigavon, GB;

Stephen Price, Harlow, GB;

Calum MacLeod, Harlow, GB;

Richard Leonard Elliott, Harlow, GB;

Phillip Smith, Harlow, GB;

Toby Jonathan Blench, Harlow, GB;

Colin Roderick O'Dowd, Craigavon, GB;

Lixin Zhang, Craigavon, GB;

Graham Peter Trevitt, Craigavon, GB;

Hazel Joan Dyke, Harlow, GB;

Assignee:

Almac Discovery Limited, Craigavon, Northern Ireland, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4188 (2006.01); A61K 31/352 (2006.01); A61K 31/357 (2006.01); A61K 31/397 (2006.01); A61K 31/4155 (2006.01); A61K 31/4162 (2006.01); A61K 31/4178 (2006.01); A61K 31/4192 (2006.01); A61K 31/422 (2006.01); A61K 31/436 (2006.01); A61K 31/437 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/5383 (2006.01); A61P 35/00 (2006.01); C07C 225/20 (2006.01); C07D 311/26 (2006.01); C07D 405/10 (2006.01); C07D 413/10 (2006.01); C07D 491/052 (2006.01); C07D 491/147 (2006.01); C07D 493/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.


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