The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2013
Filed:
May. 27, 2011
René Pellaux, Zürich, CH;
Marcel Walser, Winterthur, CH;
Andreas Jörg Meyer, Frauenfeld, CH;
Martin Held, Zürich, CH;
Sven Panke, Zürich, CH;
René Pellaux, Zürich, CH;
Marcel Walser, Winterthur, CH;
Andreas Jörg Meyer, Frauenfeld, CH;
Martin Held, Zürich, CH;
Sven Panke, Zürich, CH;
ETH Zurich, Zurich, CH;
Abstract
The invention relates to a method of fast identification and isolation of cells featuring a desired phenotype. The phenotype is coupled to the amount of gas-liberating enzymes or increased growth. The cells are encapsulated into microcapsules allowing exchange of solvents through the microcapsule wall, but retaining some or all of the gas formed by gas-liberating enzymes on contact with corresponding substrates. Microcapsules containing increased amounts of gas-liberating enzymes are starting to float and can be separated. The cells are then isolated from the microcapsules according to standard procedures.