The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2013
Filed:
Jul. 15, 2011
Daniel J Freeman, Thousand Oaks, CA (US);
Todd Juan, Newbury Park, CA (US);
Robert Radinsky, Thousand Oaks, CA (US);
Daniel J Freeman, Thousand Oaks, CA (US);
Todd Juan, Newbury Park, CA (US);
Robert Radinsky, Thousand Oaks, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
Mutations of the epidermal growth factor receptor (EGFr), of phosphatidylinositol 3'-kinase ('PI3K'), and of B-Raf are described. Methods of treating tumors containing mutated EGFr with human monoclonal antibodies against EGFr are described. Methods and kits for ascertaining the presence of one or more mutant EGFr, mutant PI3K, and/or mutant B-Raf in a sample and for treating disorders or conditions related to the presence of mutant EGFr, mutant PI3K, and/or mutant B-Raf are also described. Methods of treating tumors containing mutant EGFr, mutant PI3K, and/or mutant B-Raf are also described.