The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2013

Filed:

Nov. 05, 2010
Applicants:

Yvonne Chen, San Mateo, CA (US);

Mark Dennis, San Carlos, CA (US);

David Dornan, San Mateo, CA (US);

Kristi Elkins, San Francisco, CA (US);

Jagath Reddy Junutula, Fremont, CA (US);

Andrew Polson, San Francisco, CA (US);

Bing Zheng, Mountain View, CA (US);

Inventors:

Yvonne Chen, San Mateo, CA (US);

Mark Dennis, San Carlos, CA (US);

David Dornan, San Mateo, CA (US);

Kristi Elkins, San Francisco, CA (US);

Jagath Reddy Junutula, Fremont, CA (US);

Andrew Polson, San Francisco, CA (US);

Bing Zheng, Mountain View, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/10 (2006.01); A61K 39/44 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.


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