The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2013

Filed:

May. 31, 2006
Applicants:

Josee Roy, Memphis, TN (US);

Hezi-yamit Ayala, Windsor, CA (US);

Carol Sullivan, Fairfax, CA (US);

Mingfei Chen, Santa Rosa, CA (US);

Inventors:

Josee Roy, Memphis, TN (US);

Hezi-Yamit Ayala, Windsor, CA (US);

Carol Sullivan, Fairfax, CA (US);

Mingfei Chen, Santa Rosa, CA (US);

Assignee:

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/77 (2006.01);
U.S. Cl.
CPC ...
Abstract

In the present invention, the applicants describe methods and compositions of treating damaged cardiovascular elements and cardiovascular conditions including hypotension, atherosclerotic lesions, vulnerable plaque, and acute myocardial infarct. The applicants demonstrate the ability of a biomembrane sealing agent to accumulate on the walls of damaged blood vessels and help improving mean arterial pressure following tissue injury. The applicants describe the use of formulations comprising at least one biomembrane sealing agent and one bioactive agent for prophylactic treatment such as they could be administered concurrently to an invasive therapeutic intervention or after the insult (i.e. post-injury or post-surgery). Alternatively, these methods and compositions could be used to reduce the severity of cardiovascular diseases after onset.


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