The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2013

Filed:

Nov. 09, 2009
Applicants:

Joseph A. Kozlowski, Princeton, NJ (US);

Wensheng Yu, Edison, NJ (US);

Michael K. C. Wong, Somerset, NJ (US);

Seong Heon Kim, Livington, NJ (US);

Ling Tong, Warren, NJ (US);

Brian J. Lavey, New Providence, NJ (US);

Bandarpalle B. Shankar, Branchburg, NJ (US);

De-yi Yang, Morris Plains, NJ (US);

Robert Feltz, Washington, PA (US);

Aneta Maria Kosinski, South Amboy, NJ (US);

Guowei Zhou, Somerset, NJ (US);

Razia K. Rizvi, Bloomfield, NJ (US);

Chaoyang Dai, Acton, MA (US);

Luke Fire, Cambridge, MA (US);

Vinay Girijavallabhan, Denville, NJ (US);

Dansu LI, Reading, MA (US);

Janeta Popovici-muller, Waltham, MA (US);

Judson E. Richard, Kittery, ME (US);

Kristin E. Rosner, Watertown, MA (US);

M. Arshad Siddiqui, Newton, MA (US);

Liping Yang, Arlington, MA (US);

Inventors:

Joseph A. Kozlowski, Princeton, NJ (US);

Wensheng Yu, Edison, NJ (US);

Michael K. C. Wong, Somerset, NJ (US);

Seong Heon Kim, Livington, NJ (US);

Ling Tong, Warren, NJ (US);

Brian J. Lavey, New Providence, NJ (US);

Bandarpalle B. Shankar, Branchburg, NJ (US);

De-Yi Yang, Morris Plains, NJ (US);

Robert Feltz, Washington, PA (US);

Aneta Maria Kosinski, South Amboy, NJ (US);

Guowei Zhou, Somerset, NJ (US);

Razia K. Rizvi, Bloomfield, NJ (US);

Chaoyang Dai, Acton, MA (US);

Luke Fire, Cambridge, MA (US);

Vinay Girijavallabhan, Denville, NJ (US);

Dansu Li, Reading, MA (US);

Janeta Popovici-Muller, Waltham, MA (US);

Judson E. Richard, Kittery, ME (US);

Kristin E. Rosner, Watertown, MA (US);

M. Arshad Siddiqui, Newton, MA (US);

Liping Yang, Arlington, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 295/03 (2006.01); C07D 241/20 (2006.01); C07D 211/30 (2006.01); C07D 213/46 (2006.01); C07D 403/06 (2006.01); C07D 203/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF—or combinations thereof.


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