The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2013
Filed:
May. 26, 2010
Krishnamurti DE Morais Carvalho, Fortaleza, BR;
Dòris Maria Fernandes Carvalho, Fortaleza, BR;
Maria Denise Fernandes Carvalho, Fortaleza, BR;
Ogari DE Castro Pacheco, Itapira, BR;
Roberto Carlos Debom Moreira, Itapira, BR;
Krishnamurti De Morais Carvalho, Fortaleza, BR;
Dòris Maria Fernandes Carvalho, Fortaleza, BR;
Maria Denise Fernandes Carvalho, Fortaleza, BR;
Ogari de Castro Pacheco, Itapira, BR;
Roberto Carlos Debom Moreira, Itapira, BR;
Cristalia Produtos Quimicos Farmaceuticos Ltda., Itapira, BR;
Genpharma Consultoria Farmaceutica E Genetica Ltda., Fortaleza, BR;
Abstract
The present invention is directed to the use of telocinobufagin, or its pharmaceutically acceptable derivatives, in the manufacture of a medicament for the treatment or prevention of acute and chronic pains. The present invention also refers to a pharmaceutical composition comprising an effective amount of telocinobufagin; also provides a method to induce analgesia in response to acute and chronic pains that comprehends administering an effective amount of telocinobufagin to human beings or animals. According to the outcomes of in vivo assays, telocinobufagin is more potent than morphine, though without presenting the known side effects of opioids. In addition, in vivo and in vitro essays showed that TBC does not present cardiotoxicity.