The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2013
Filed:
Mar. 01, 2010
Markus Stoffel, Zurich, CH;
Muthiah Manoharan, Weston, MA (US);
Kallanthottathil G Rajeev, Wayland, MA (US);
Markus Stoffel, Zurich, CH;
Muthiah Manoharan, Weston, MA (US);
Kallanthottathil G Rajeev, Wayland, MA (US);
The Rockefeller University, New York, NY (US);
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
This invention relates generally to chemically modified oligonuceotides useful for modulating expression of microRNAs and pre-microRNAs. More particularly, the invention relates to single stranded chemically modified oligonuceotides for inhibiting microRNA and pre-microRNA expression and to methods of making and using the modified oligonucleotides. Also included in the invention are compositions and methods for silencing microRNAs in the central nervous system.