The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2013
Filed:
Jan. 21, 2011
Clive Robinson, London, GB;
Jihui Zhang, London, GB;
David Ronald Garrod, Manchester, GB;
Trevor Robert Perrior, Cambridge, GB;
Gary Karl Newton, Cambridge, GB;
Kerry Jenkins, Cambridge, GB;
Rebekah Elisabeth Beevers, Cambridge, GB;
Meriel Ruth Major, Cambridge, GB;
Mark Richard Stewart, Cambridge, GB;
Clive Robinson, London, GB;
Jihui Zhang, London, GB;
David Ronald Garrod, Manchester, GB;
Trevor Robert Perrior, Cambridge, GB;
Gary Karl Newton, Cambridge, GB;
Kerry Jenkins, Cambridge, GB;
Rebekah Elisabeth Beevers, Cambridge, GB;
Meriel Ruth Major, Cambridge, GB;
Mark Richard Stewart, Cambridge, GB;
St George's Hosptial Medical School, London, GB;
The University of Manchester, Manchester, GB;
Abstract
The present invention pertains generally to the field of therapeutic compounds and more specifically to certain pyruvamide compounds of the formula (X) (for convenience, collectively referred to herein as 'PVA compounds'), which, inter alia, inhibit a dust mite Group 1 peptidase allergen (e.g., Der p 1, Der f 1, Eur m 1). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit a dust mite Group 1 peptidase allergen, and in the treatment of diseases and disorders that are mediated by a dust mite Group 1 peptidase allergen; that are ameliorated by the inhibition of a dust mite Group 1 peptidase allergen; asthma; rhinitis; allergic conjunctivitis; atopic dermatitis; an allergic condition which is triggered by dust mites; an allergic condition which is triggered by a dust mite Group 1 peptidase allergen; and canine atopy.