The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2013
Filed:
Dec. 05, 2012
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Josef Endl, Weilheim, DE;
Erhard Kopetzki, Penzberg, DE;
Oliver Ploettner, Munich, DE;
Ursula Schwarz, Eurasburg, DE;
Georg Tiefenthaler, Sindelsdorf, DE;
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The current invention describes a nucleic acid comprising in a 5' to 3′ direction a) a first nucleic acid encoding a heterologous polypeptide without an in frame stop codon, b) a second nucleic acid beginning with a 5′ splice donor site and terminated by a 3′ splice acceptor site comprising an in frame translational stop codon and a polyadenylation signal, and c) a nucleic acid encoding i) at least a fragment of a transmembrane domain, or ii) a signal peptide for a GPI-anchor.