The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2013
Filed:
Dec. 22, 2009
Jan Metske Van Der Laan, Breda, NL;
Harold Monro Moody, Gulpen, NL;
Richard Kerkman, Zandvoort, NL;
Thomas Van Der Does, Wilnis, NL;
Jan Metske Van Der Laan, Breda, NL;
Harold Monro Moody, Gulpen, NL;
Richard Kerkman, Zandvoort, NL;
Thomas Van Der Does, Wilnis, NL;
DSM Sinochem Pharmaceuticals Netherlands B.V., Delft, NL;
Abstract
The present invention relates to a mutant prokaryotic penicillin G acylase derived from a wild-type penicillin G acylase characterized in that the mutant is having an amino acid substitution at one or more amino acid positions selected from the group consisting of amino acid positions A3, A77, A90, A144 A192, B24, B109, B148, B313, B460 and B488 according to the amino acid numbering of thepenicillin G acylase having the amino acid sequence depicted in SEQ ID No: 1.