The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2013

Filed:

Jul. 08, 2008
Applicants:

Shoichi Naito, Toyonaka, JP;

Junji Onoda, Toyonaka, JP;

Akira Yamauchi, Toyonaka, JP;

Yoshito Numata, Toyonaka, JP;

Junji Kishono, Toyonaka, JP;

Inventors:

Shoichi Naito, Toyonaka, JP;

Junji Onoda, Toyonaka, JP;

Akira Yamauchi, Toyonaka, JP;

Yoshito Numata, Toyonaka, JP;

Junji Kishono, Toyonaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C07K 16/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

A neutralizing monoclonal antibody specifically reacting with MMP13, a method of neutralizing enzyme activity of MMP13 and an immunological measuring method each using the antibody, as well as a diagnostic agent and a pharmaceutical composition containing the antibody, are provided. Various antibodies to MMP13 have been hitherto obtained, but an antibody having neutralizing activity against MMP13 has not been obtained. The present inventors intensively studied, as a result, found out a neutralizing antibody having specificity for MMP13, resulting in completion of the present invention.


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