The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2013

Filed:

Sep. 11, 2009
Applicants:

Péter Mátyus, Budapest, HU;

Kálmán Magyar, Budapest, HU;

Marjo Pihlavisto, Kaarina, FI;

Klára Gyires, Budapest, HU;

Norbert Haider, Vienna, AT;

Yinghua Wang, Shanghai, CN;

Patrick Woda, Vienna, AT;

Petra Dunkel, Budapest, HU;

Éva Tóth-sarudy, Budapest, HU;

György Túrós, Budapest, HU;

Inventors:

Péter Mátyus, Budapest, HU;

Kálmán Magyar, Budapest, HU;

Marjo Pihlavisto, Kaarina, FI;

Klára Gyires, Budapest, HU;

Norbert Haider, Vienna, AT;

Yinghua Wang, Shanghai, CN;

Patrick Woda, Vienna, AT;

Petra Dunkel, Budapest, HU;

Éva Tóth-Sarudy, Budapest, HU;

György Túrós, Budapest, HU;

Assignee:

Semmelweis Egyetem, Budapest, HU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/76 (2006.01); A61K 31/42 (2006.01); C07D 263/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds of general formula (i) having an oxime moiety or a pharmaceutically acceptable salt, hydrate or solvate thereof and its use for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1), a pharmaceutical composition comprising the compound or a salt, hydrate or solvate thereof as an active ingredient, a method for the prevention or the treatment of a SSAO/VAP-1 related disease, said diseases including acute or chronic inflammatory diseases, diseases related to carbohydrate metabolism, diabetes-associated complications, diabetic retinopathy and macular oedema, diseases related to adipocyte or smooth muscle dysfunctions, neurodegenerative diseases and vascular diseases.


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