The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2013
Filed:
Jul. 23, 2008
Applicants:
Joseph B. Santella, Springfield, PA (US);
John Hynes, Washington Crossing, PA (US);
Daniel S. Gardner, Furlong, PA (US);
Inventors:
Joseph B. Santella, Springfield, PA (US);
John Hynes, Washington Crossing, PA (US);
Daniel S. Gardner, Furlong, PA (US);
Assignee:
Bristol-Myers Squibb Company, Priceton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 405/06 (2006.01); C07D 401/12 (2006.01); C07D 211/52 (2006.01); A61K 31/501 (2006.01); A61K 31/497 (2006.01); A61K 31/4545 (2006.01); A61K 31/454 (2006.01); A61K 31/451 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present application describes modulators of MIP-1 of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein m, Q, T, W, Z, R1, R3, R4, R5, R5a and R5b, are as set forth above. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using the modulators are disclosed.