The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2013

Filed:

Aug. 09, 2010
Applicants:

Leyi Gong, San Mateo, CA (US);

Xiaochun Han, Cedar Grove, NJ (US);

Ferenc Makra, Palo Alto, CA (US);

Wylie Solang Palmer, Morristown, NJ (US);

Lubica Raptova, Sunnyvale, CA (US);

Inventors:

Leyi Gong, San Mateo, CA (US);

Xiaochun Han, Cedar Grove, NJ (US);

Ferenc Makra, Palo Alto, CA (US);

Wylie Solang Palmer, Morristown, NJ (US);

Lubica Raptova, Sunnyvale, CA (US);

Assignee:

Roche Palo Alto LLC, San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein p, q, Y', r, R, R, X, X, X, X, and Xare as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.


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