The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2013
Filed:
Apr. 11, 2007
Alberto Cerri, Milan, IT;
Giorgio Fedrizzi, Treviglio, IT;
Alessandra Benicchio, Lainate, IT;
Giuseppe Bianchi, Milan, IT;
Patrizia Ferrari, Varese, IT;
Mauro Gobbini, Mercallo, IT;
Rosamaria Micheletti, Milan, IT;
Marco Pozzi, Omega, IT;
Piero Enrico Scotti, Cesano Maderno, IT;
Alberto Cerri, Milan, IT;
Giorgio Fedrizzi, Treviglio, IT;
Alessandra Benicchio, Lainate, IT;
Giuseppe Bianchi, Milan, IT;
Patrizia Ferrari, Varese, IT;
Mauro Gobbini, Mercallo, IT;
Rosamaria Micheletti, Milan, IT;
Marco Pozzi, Omega, IT;
Piero Enrico Scotti, Cesano Maderno, IT;
Abstract
Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart failure and hypertension. The compounds are inhibitors of the enzymatic activity of the Na+, K+-ATPase. They are useful for the preparation of a medicament for the treatment of a disease caused by the hypertensive effects of endogenous ouabain, such as renal failure progression in autosomal dominant polycystic renal disease (ADPKD), preeclamptic hypertension and proteinuria and renal failure progression in patients with adducin polymorphisms.