The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2013
Filed:
Apr. 30, 2012
Nelly Tsvetkova, Vallejo, CA (US);
Omkar Joshi, Albany, CA (US);
Paul Wu, Orinda, CA (US);
Deqian Wang, Concord, CA (US);
Arnaud Desponds, Yverdon-les-Bains, CH;
Nelly Tsvetkova, Vallejo, CA (US);
Omkar Joshi, Albany, CA (US);
Paul Wu, Orinda, CA (US);
Deqian Wang, Concord, CA (US);
Arnaud Desponds, Yverdon-les-Bains, CH;
Bayer Healthcare LLC, Tarrytown, NY (US);
Abstract
The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of −56° C. or higher.