The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2013

Filed:

Feb. 25, 2013
Applicants:

Hsing-wen Sung, Hsinchu, TW;

Ha Giang Thi Nguyen, Hsinchu, TW;

Fang Yi Su, Hsinchu, TW;

Li-wen Hsu, Hsinchu, TW;

Er-yuan Chung, Hsinchu, TW;

Hosheng Tu, Newport Beach, CA (US);

Inventors:

Hsing-Wen Sung, Hsinchu, TW;

Ha Giang Thi Nguyen, Hsinchu, TW;

Fang Yi Su, Hsinchu, TW;

Li-Wen Hsu, Hsinchu, TW;

Er-Yuan Chung, Hsinchu, TW;

Hosheng Tu, Newport Beach, CA (US);

Assignees:

GP Medical, Inc., Newport Beach, CA (US);

National Tsing Hua University, Hsinchu, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention discloses a composition of nanoparticles composed of positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one tumor necrosis factor inhibitor for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.


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