The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Dec. 01, 2008
Elena Barbanti, Cologno Monzese, IT;
Laura Faravelli, Garbagnate Milanese, IT;
Patricia Salvati, Arese, IT;
Renato Canevotti, Chignolo D'Isola, IT;
Francesco Ponzini, Chignolo D'Isola, IT;
Elena Barbanti, Cologno Monzese, IT;
Laura Faravelli, Garbagnate Milanese, IT;
Patricia Salvati, Arese, IT;
Renato Canevotti, Chignolo D'Isola, IT;
Francesco Ponzini, Chignolo D'Isola, IT;
Newron Pharmaceuticals, S.p.A., Bresso, IT;
Abstract
A process for obtaining therapeutically active 2-[4-(3- and 2-(fluorobenzyloxy)benzylamino]-propanamides and their salts with pharmaceutically acceptable acids with a high degree of purity, i.e. with a content of dibenzyl derivatives impurities lower than 0.03% by weight. The process is carried out by submitting a Schiff base intermediate to a reduction reaction with a reducing agent in an amount of organic solvent to allow the formation (and presence during a substantial portion of the reduction reaction) of a suspension of the Schiff base.